Terminal AI for working biologists.

Wet-lab questions, sequence ops, paper lookups, fine-tuning runs — all from your terminal. Drag-drop a FASTA, paste a Western image, ask anything.

What it does

• Chat with Claude Sonnet, with bio-specific routing and skills (BLAST, UniProt, PubMed, FASTA stats, codon translate).
• Drag-drop files (FASTA, CSV, PDF, gel images) into any chat — they're sent as context.
• Run a coding agent locally to clone repos, write scripts, run them in a sandbox.
• Schedule recurring research with /cron.
• Optional fine-tune flow into HuggingFace.

What you need

• An Anthropic API key (new accounts get $5 free credit; ~$0.01–$0.05 per question).
• Python 3.11+ (the installer auto-installs via uv if you don't have it).

After install

• Run bios to launch the REPL — first time prompts for your API key.
• Or one-shot: bios chat "what's the typical Tm for a 20bp primer with 50% GC?"
• Type / in the REPL to see all commands.
• Upgrade: re-run the curl command.
• Uninstall: rm -rf ~/.local/share/bios ~/.local/bin/bios